myHMB® Hydroxy Methyl Butyrate (HMB)
BCAA Leucine Support Recovery Metabolite
our cornerstone of recovery
The founder of Strenduro (Clean Energy Foods) was pleased to find that a high-quality HMB powder was available for formulation. Not only was this molecule an important piece of an academic puzzle that few people seemed to be able to discuss (how does a muscle tell itself to adapt to work?) but knowing about it had real-world practicality. As a rower, the founder was always putting out a lot of muscular effort 6 days per week, and 7 days per week he was sore and damaged, in need of rest and recovery.
Even before his original Sophomore Paper, he discovered a product with HMB that was well-reviewed and tried it. Using it, he noticed changes to his own recovery in just a few short days. The key ingredient was myHMB® brand of Calcium Hydroxy Methyl Butyrate. myHMB is now part of an upgraded stack in Strenduro. See what it can do for you!
For over 200 years, the United States Pharmacopeia (USP) has been an independent scientific organization that focuses on building trust in safe pure medicines, dietary supplements, and food ingredients. The public quality standards USP sets helps to protect consumers and improve the health of people around the world. USP Verified means the quality and reliability of the manufacturing process and the lot purity of the ingredient myHMB® is recognized from the participating manufacturer TSI. (See link in Verified logo)
Informed Sport (at wetestyoutrust.com) is a global testing and certification program for sports and nutritional supplements. It has been a key referee in identifying ingredients adulterated and contaminated by banned substances. myHMB® has been certified to contain no banned substances by Informed Sport and is the only HMB on the market that has been approved as an Informed Ingredient. (See link in Informed logo)
Some Small Amount of HMB Research
- Wilson, et al., "International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)." (2013) J. ISSN
- Shirato, et al., "Effects of combined ß-hydroxy-ß-methylbutyrate (HMB) and whey protein ingestion on symptoms of eccentric exercise-induced muscle damage." (2022) J. ISSN
- Calleja-González, et al., "Effect Of ß-hydroxy-ß-methylbutyrate And Creatine Supplementation On Muscle Recovery In Elite Rowers As Measured By Anabolic And Catabolic Hormones." (2018) Med. Sci. Sports Exer.
- Durkalec-Michalski, et al., "The efficacy of a ß-hydroxy-ß-methylbutyrate supplementation on physical capacity, body composition and biochemical markers in elite rowers: a randomized, double-blind, placebo-controlled crossover study." (2015) J. Int. Soc. Sports Nutr.
- Vukovich, et al., "Effect of ß-hydroxy-ß-methylbutyrate (HMB) on VO2 peak and maximal lactate in endurance trained cyclists." (2001) J. Strength Cond. Res.
- Ra, et al., "Effect of BCAA supplement timing on exercise-induced muscle soreness and damage: a pilot placebo-controlled double-blind study." (2018) J. Sports Med. Phys. Fit.
- Duan, et al., "ß-hydroxy-ß-methyl butyrate, but not alpha-ketoisocaproate and excess leucine, stimulates skeletal muscle protein metabolism in growing pigs fed low-protein diets." (2019) J. Funct. Foods
- Hill, et al., "ß-Hydroxy-ß-methylbutyrate (HMB) stimulates mammalian target of rapamycin complex 1 (mTORc1) signaling via a phosphatidylinositol-3-kinase (PI3K)-dependent pathway." (2011) FASEB J.
- Knitter, et al., "Effects of ß-hydroxy-ß-methylbutyrate on muscle damage after a prolonged run" (2000) J. App. Phys.
- Wilson, et al., "Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review." (2008) Nutr. Metab.
- Nissen, "ß-Hydroxy-ß-Methylbutyrate." (2004) in "Nutritional Ergogenic Aides," pp120-139, Wolinsky, et al., eds.
- Nissen, et al., "Effect of leucine metabolite ß-hydroxy-ß-methylbutyrate on muscle metabolism during resistance-exercise training." (1996) J. App. Phys.
- Miramonti, et al., "Effects of 4 Weeks of High-Intensity Interval Training and ß-Hydroxy-ß-Methylbutyric Free Acid Supplementation on the Onset of Neuromuscular Fatigue." (2016) J. Strength Cond. Res.
- Wilkinson, et al., "Impact of the calcium form of ß-hydroxy-ß-methylbutyrate upon human skeletal muscle protein metabolism." (2018) Clin. Nutr.
- Cavallucci, et al., "The Leucine Catabolite and Dietary Supplement ß-Hydroxy-ß-Methyl Butyrate (HMB) as an Epigenetic Regulator in Muscle Progenitor Cells." (2021) Metabolites
- Zhong, et al., "ß-hydroxy-ß-methylbutyrate (HMB) improves mitochondrial function in myocytes through pathways involving PPARß/δ and CDK4." (2019) Nutrition
- Narkar, et al., "AMPK and PPARδ Agonists Are Exercise Mimetics" (2008) Cell
- Kreider, et al., "Effects of calcium beta-hydroxy-beta-methylbutyrate (HMB) supplementation during resistance-training on markers of catabolism, body composition and strength." (1999) Int. J. Sports Med.
- Columbus, et al., "Leucine is a major regulator of muscle protein synthesis in neonates." (2015) Amino Acids
- Tsuchiya, et al., "Two and Four Weeks of ß-Hydroxy-ß-Methylbutyrate (HMB) Supplementations Reduce Muscle Damage Following Eccentric Contractions." (2018) J. ISSN
- Kraemer, et al., "The Addition of Beta-hydroxy-beta-methylbutyrate and Isomaltulose to Whey Protein Improves Recovery from Highly Demanding Resistance Exercise." (2015) J. Am. Coll. Nutr.
THE Other Ingredients
BETA-ALANINE
gets in, makes carnosine happen.
Working muscle breaks down ATP. This process makes acid (the sizzle). The only way to manage acid is to pick up and re-use ATP breakdown products. Muscles rely on Carnosine to scavenge those breakdown products and control the sizzle. Beta-Alanine makes Carnosine happen.
Creatine Monohydrate
the most researched ENDURANCE compound.
Creatine Monohydrate has been researched for athletic performance since the 1970s. Like Carnosine, Creatine scavenges ATP breakdown products and helps control the sizzle. Together, these two biochemicals cover the muscle cell compartments, manage pH and elevate ATP in work.